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galT [2019-07-15 10:33:37]
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galT [2019-07-15 10:33:37]

galactose-1-phosphate uridylyltransferase
locus
BSU_38190
pI
5.62
mw
58.44 kDa
protein length
513 aa Sequence Blast
gene length
1542 bp Sequence Blast
function
galactose utilization
product
galactose-1-phosphate uridylyltransferase
essential
no
ec
2.7.7.12
synonyms
ipa-36d
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.8|Utilization of galactose]

    • Gene

    Coordinates
    3,919,093 3,920,634

    The protein

    Catalyzed reaction/ biological activity

  • UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose (according to Swiss-Prot)

    • Protein family

  • galactose-1-phosphate uridylyltransferase type 2 family (according to Swiss-Prot)

    • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|36930CC6FDFCA23D43E264FEA375B78A1434E1BD|galK]-[gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]
    description
    [Pubmed|9353933]

    regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|10666464], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]

    • regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
    • view in new tab

    genes
    [gene|C3D87DAA8DB124D50D2C2B2D424C9608C0DE067F|ywcC]-[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]-[gene|36930CC6FDFCA23D43E264FEA375B78A1434E1BD|galK]-[gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]
    description
    [Pubmed|22383849,22893383]

    regulation

  • repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
    • view in new tab

    Biological materials

    Mutant

  • BKE38190 ([gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAGATGTTCAATAATACTCA, downstream forward: _UP4_TAGGGTTGAGGCTTTTTCGA
  • BKK38190 ([gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38190 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAGATGTTCAATAATACTCA, downstream forward: _UP4_TAGGGTTGAGGCTTTTTCGA

    • References

  • 9353933,10666464,22383849,22893383